Technical Note

The Delfin VapoMeter®: The Benefits of Closed-Chamber Measurement Principle in TEWL Measurements

Technical Note
VapoMeter

The Delfin VapoMeter has many important benefits for transepidermal water loss (TEWL) measurements. The VapoMeter is extremely practical and fast to use, and it operates with the closed-chamber measurement principle, which eliminates several environmental factors from the measurement. The VapoMeter’s hand-held portable design and wireless capability makes it extremely simple to use in a range of clinical and research applications.

The core of the VapoMeter is a sensitive humidity sensor in a cylindrical measurement chamber. The closed chamber principle of the VapoMeter ensures that the measurements and results are not affected by ambient airflows. Furthermore, the measurement principle allows measurements at all angles and at virtually all body sites.

The Delfin VapoMeter offers many benefits for TEWL measurements compared to conventional open-chamber method. The devices that are open to ambient environment are commonly described as open-chamber devices, whereas the devices that are enclosed from the ambient environment are referred as closed-chamber devices.

The literature-based benefits of the closed-chamber Delfin VapoMeter over the conventional open-chamber method are presented in a below table.

Delfin VapoMeter

Conventional open-chamber method

Unaffected by ambient airflows like breathing, air conditioning, etc. Opening the door, persons walking by or breathing towards / close to probe during the measurement disturbs vapor gradient and may cause incorrect TEWL values
Orientation free measurements – can be used at any angle Natural air convection requires that the probe has to be placed on the horizontal skin surface, i.e. on the upper surface of the measurement object
No saturation at high TEWL values Vapor gradient methods tends to underestimate high TEWL values
Measurement time 7 – 12 seconds

 

Stabilizing vapor gradient means slower measurements (~20 seconds)

The Delfin VapoMeter has been used in hundreds of studies related to the skin and there are a lot of reference publications available. By offering a range of adapters of different sizes, the VapoMeter is also fully applicable for in-vitro studies.

Accurate measurement of transepidermal water loss (TEWL) is important for a wide range of clinical and personal care applications and for claims validation. The measurement of TEWL provides key information about the skin barrier function and skin condition. The skin barrier function is an important indicator of many skin conditions, making it a regularly studied topic in skin research and personal care R&D.

The VapoMeter has been used in a wide range of applications:

  • Skin barrier function
  • Efficacy testing
  • Skin irritation
  • Hyperhidrosis
  • Wound healing
  • In vitro studies
  • Veterinary studies

The VapoMeter® is a registered trademark of the Delfin Technologies Ltd.

 

Delfin Technologies Ltd

info@delfintech.com

www.delfintech.com

The Delfin VapoMeter® for transepidermal water loss (TEWL) and evaporation studies

Technical Note
VapoMeter

The Delfin VapoMeter® for transepidermal water loss (TEWL) and evaporation studies

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