VapoMeter articles

VapoMeter in scientific articles

The VapoMeter has been used widely for TEWL and penetration studies both in-vivo and in-vitro. 

Below is a list of references for the scientific studies related to the VapoMeter.

Transepidermal water loss TEWL, Skin barrier function, Penetration studies

The Effects of Regional Climate and Aging on Seasonal Variations in Chinese Women’s Skin Characteristics Kim E., Han J., Park H., Kim M., Kim B., Yeon J., Wei L., Wei L. and Lee H.
JCDSA, 7:164-172, 2017.

Effect of Physiological Changes in the Skin on Systemic Absorption of Tacrolimus Following Topical Application in Rats Hazama Y., Maekawa T., Miki R., Oshima S., Egawa Y., Morimoto K. and Sekia T.
Biol Pharm Bull, 39:343-352, 2016.

Effects of Phosphoryl Oligosaccharides of Calcium (POs-Ca) on Epidermal Cells and Human Skin Sambe H., Sugimoto K., Nomura K. and Kuriki T.
J Appl Glycosci, 62:107-113, 2015.

The Effects of Regional Climate and Aging on Seasonal Variations in Chinese Women’s Skin Characteristics Kim E., Han J., Park H., Kim M., Kim B., Yeon J., Wei L., Wei L. and Lee H.
JCDSA, 7:164-172, 2017.

Effect of Physiological Changes in the Skin on Systemic Absorption of Tacrolimus Following Topical Application in Rats Hazama Y., Maekawa T., Miki R., Oshima S., Egawa Y., Morimoto K. and Sekia T.
Biol Pharm Bull, 39:343-352, 2016.

Effects of Phosphoryl Oligosaccharides of Calcium (POs-Ca) on Epidermal Cells and Human Skin Sambe H., Sugimoto K., Nomura K. and Kuriki T.
J Appl Glycosci, 62:107-113, 2015.

 

Skin irritation

The Effects of Regional Climate and Aging on Seasonal Variations in Chinese Women’s Skin Characteristics Kim E., Han J., Park H., Kim M., Kim B., Yeon J., Wei L., Wei L. and Lee H.
JCDSA, 7:164-172, 2017.

Effect of Physiological Changes in the Skin on Systemic Absorption of Tacrolimus Following Topical Application in Rats Hazama Y., Maekawa T., Miki R., Oshima S., Egawa Y., Morimoto K. and Sekia T.
Biol Pharm Bull, 39:343-352, 2016.

Effects of Phosphoryl Oligosaccharides of Calcium (POs-Ca) on Epidermal Cells and Human Skin Sambe H., Sugimoto K., Nomura K. and Kuriki T.
J Appl Glycosci, 62:107-113, 2015.

The Effects of Regional Climate and Aging on Seasonal Variations in Chinese Women’s Skin Characteristics Kim E., Han J., Park H., Kim M., Kim B., Yeon J., Wei L., Wei L. and Lee H.
JCDSA, 7:164-172, 2017.

Effect of Physiological Changes in the Skin on Systemic Absorption of Tacrolimus Following Topical Application in Rats Hazama Y., Maekawa T., Miki R., Oshima S., Egawa Y., Morimoto K. and Sekia T.
Biol Pharm Bull, 39:343-352, 2016.

Effects of Phosphoryl Oligosaccharides of Calcium (POs-Ca) on Epidermal Cells and Human Skin Sambe H., Sugimoto K., Nomura K. and Kuriki T.
J Appl Glycosci, 62:107-113, 2015.

Effect of skin care, treatment, nutrition

The Effects of Regional Climate and Aging on Seasonal Variations in Chinese Women’s Skin Characteristics Kim E., Han J., Park H., Kim M., Kim B., Yeon J., Wei L., Wei L. and Lee H.
JCDSA, 7:164-172, 2017.

Effect of Physiological Changes in the Skin on Systemic Absorption of Tacrolimus Following Topical Application in Rats Hazama Y., Maekawa T., Miki R., Oshima S., Egawa Y., Morimoto K. and Sekia T.
Biol Pharm Bull, 39:343-352, 2016.

Effects of Phosphoryl Oligosaccharides of Calcium (POs-Ca) on Epidermal Cells and Human Skin Sambe H., Sugimoto K., Nomura K. and Kuriki T.
J Appl Glycosci, 62:107-113, 2015.

The Effects of Regional Climate and Aging on Seasonal Variations in Chinese Women’s Skin Characteristics Kim E., Han J., Park H., Kim M., Kim B., Yeon J., Wei L., Wei L. and Lee H.
JCDSA, 7:164-172, 2017.

Effect of Physiological Changes in the Skin on Systemic Absorption of Tacrolimus Following Topical Application in Rats Hazama Y., Maekawa T., Miki R., Oshima S., Egawa Y., Morimoto K. and Sekia T.
Biol Pharm Bull, 39:343-352, 2016.

Effects of Phosphoryl Oligosaccharides of Calcium (POs-Ca) on Epidermal Cells and Human Skin Sambe H., Sugimoto K., Nomura K. and Kuriki T.
J Appl Glycosci, 62:107-113, 2015.

Scalp, lip and nail measurements

The Effects of Regional Climate and Aging on Seasonal Variations in Chinese Women’s Skin Characteristics Kim E., Han J., Park H., Kim M., Kim B., Yeon J., Wei L., Wei L. and Lee H.
JCDSA, 7:164-172, 2017.

Effect of Physiological Changes in the Skin on Systemic Absorption of Tacrolimus Following Topical Application in Rats Hazama Y., Maekawa T., Miki R., Oshima S., Egawa Y., Morimoto K. and Sekia T.
Biol Pharm Bull, 39:343-352, 2016.

Effects of Phosphoryl Oligosaccharides of Calcium (POs-Ca) on Epidermal Cells and Human Skin Sambe H., Sugimoto K., Nomura K. and Kuriki T.
J Appl Glycosci, 62:107-113, 2015.

The Effects of Regional Climate and Aging on Seasonal Variations in Chinese Women’s Skin Characteristics Kim E., Han J., Park H., Kim M., Kim B., Yeon J., Wei L., Wei L. and Lee H.
JCDSA, 7:164-172, 2017.

Effect of Physiological Changes in the Skin on Systemic Absorption of Tacrolimus Following Topical Application in Rats Hazama Y., Maekawa T., Miki R., Oshima S., Egawa Y., Morimoto K. and Sekia T.
Biol Pharm Bull, 39:343-352, 2016.

Effects of Phosphoryl Oligosaccharides of Calcium (POs-Ca) on Epidermal Cells and Human Skin Sambe H., Sugimoto K., Nomura K. and Kuriki T.
J Appl Glycosci, 62:107-113, 2015.

Wound healing

Iontophoretic drug delivery for the treatment of scars
Manda P., Angamuthu M., Hiremath S.R., Raman V. and Murthy S.N.
J Pharm Sci, Jun;103(6):1638-42, 2014.

Quantitative Evaluation of Maceration in Venous Leg Ulcers by Transepidermal Water Loss (TEWL) Measurement
Dini V., Barbanera S. and Romanelli M.
Int J Low Extrem Wounds, May 25;13(2):116-119, 2014.

Flii neutralizing antibodies improve wound healing in porcine preclinical studies
Jackson J.E., Kopecki Z., Adams D.H. and Cowin A.J.
Wound Repair Regen, Vol 20(4):523–536, 2012.

Human cell-conditioned media produced under embryonic-like conditions result in improved healing time after laser resurfacing
Zimber M.P., Mansbridge J.N., Taylor M., Stockton T., Hubka M., Baumgartner M., Rheins L., Hubka K., Brandt E.N., Kellar R. and Naughton G.K.
Aesthetic Plast Surg, Vol 36(2):431-437, 2012.

Comparison of a sealed, polymer foam biodegradable temporizing matrix against integra® dermal regeneration template in a porcine wound model
Greenwood J.E. and Dearman B.L.
J Burn Care Res, Jan-Feb;33(1):163-173, 2012.

Epidermal wound healing in severe sepsis and septic shock in humans
Koskela M., Gäddnäs F., Ala-Kokko T.I., Laurila J.J., Saarnio J., Oikarinen A. and Koivukangas V.
Crit Care, Jun;13(3):R100, 2009.

Instrumental evaluation of the protective effects of a barrier film on surrounding skin in chronic wounds
Dini V., Salibra F., Brilli C. and Romanelli M.
Wounds, Sept;20:254-257, 2008.

Use of nanotechnology-designed footsock in the management of preulcerative conditions in the diabetic foot: results of a single, blind randomized study
Banchellini E., Macchiarini S., Dini V., Rizzo L., Tedeschi A., Scatena A., Goretti C., Campi F., Romanelli M. and Alberto P.
Int J Low Extrem Wounds, 7:2:82-87, 2008.

Abstracts

Moisture vapour transmission rate – How is this affected by wound fluid viscosity?
Adams S., Pritchard D. and Rogers J.
Poster presented at European Wound Management Association 2009, Finland.

Evaluation of maceration by trans epidermal water loss (TEWL) in patients with venous leg ulcers
Dini V., Salibra F., Brilli C., Bertone M. and Romanelli M.
Sumposium on Advanced Wound Care & Medical Reseach Forum on Wound Repair, p. 128, 2006.

Skin surface water loss SSWL

Validating a new device for measuring tear evaporation rates
Rohit A., Ehrmann K., Naduvilath T., Willcox M. and Stapleton F.
Ophthalmic Physiol Opt, Jan;34(1):53-62, 2014.

Abstracts

Evaluation of long-term performance utilizing a high absorbency adult incontinence brief in a long-term care setting and its impact on overall skin health.
Kennedy-Evans K.L., Salomon S. and Barba K.
Innovating for Continence: The Engineering Challenge 2011, Apr 11-13, 2011, Lincolnshire, Illinois.

The effect of different incontinence “gel-based” briefs on skin barrier function in institutionalised adults.
Salomon S., Milne C.T., Saucier D. and Barba K.
Innovating for Continence: The Engineering Challenge 2011, Apr 11-13, 2011, Lincolnshire, Illinois.

Measurement of skin hydration in the diapered area of infants with a closed chamber TEWL meter
Alanen, E., Wiesemann, F., Nuutinen, J. and Lahtinen, T.
Skin Res Technol, Vol 9(2): 199, 2003.

Transonychial water loss TOWL

Tape stripping on a human nail: quantification of removal
Tudela E., Lamberbourg A., Diaz A.C., Zhai H. and Maibach H.I.
Skin Res Technol, 14:472–477, 2008.

The use of an extended ventilation tube as a countermeasure for EVA-associated upper extremity medical issues
Jones J.A., Hoffman R.B., Buckland D.A., Harvey C.M., Bowen C.K., Hudy C.E. Strauss S., Novak J. and Gernhardt M.L.
Acta Astronaut, 63:763-768, 2008.

Water loss through lip, nail, eyelid skin, scalp skin and axillar skin measured with a closed-chamber evaporation principle
Nuutinen J., Harvima I., Lahtinen M.-R. and Lahtinen T.
Br J Dermatol, 148:839-841, 2003.

Physiological and Sympathetic skin response, Hyperhidrosis

Botulinum toxin B in the treatment of craniofacial hyperhidrosis
Karlqvist M., Rosell K., Rystedt A., Hymnelius K. and Swartling C.
J Eur Acad Dermatol Venereol, epub Oct 3, 2013.

Objective evaluation of plantar hyperhidrosis after sympathectomy
Wolosker N., Ishy A., Yazbek G., de Campos J.R.B., Kauffman P., Puech-Lea P. and Jatene F.B.
CLINICS, 68(3):311-315, 2013.

Effects of water nanodroplets on skin moisture and viscoelasticity during air-conditioning
Ohno H., Nishimura N., Yamada K., Shimizu Y., Iwase S., Sugenoya J. and Sato M.
Skin Res Technol, epub Apr 17, 2013.

Botulinum toxin type A and B improve quality of life in patients with axillary and palmar hyperhidrosis
Rosell K., Hymnelius K. and Swartling C.
Acta Derm Venereol, May;93(3):335-9, 2013.

Quantitative assessment of the intensity of palmar and plantar sweating in patients with primary palmoplantar hyperhidrosis
Sakiyama B.Y.P., Monteiro T.V., Ishy A., de Campos J.R.M., Kauffman P. and Wolosker N.
J Bras Pneumol, 38(5):573-8, 2012.

Long-term efficacy of liposuction in patients with axillary hyperhidrosis
Boeni R.
American J Cosmetic Surgery, Vol. 29(3):187-189, 2012.

Effect of duodenal levodopa infusion on blood pressure and sweating
Pursiainen V., Lyytinen J. and Pekkonen E.
Acta Neurol Scand, Oct;126(4):e20-4, 2012.

Psychological stress and transepidermal water loss in atopic dermatitis: preliminary results
Kepska A., Haftek M., Nosbaum A., Pralong P., Nicolas J.-F., Berard F., Ograczyk A. and Zalewska-Janowska A.
Postep Derm Alergol, XXIX,4:263-266, 2012.

Definitive diagnosis and management of axillary hyperhidrosis: the VapoMeter and suction-assisted arthroscopic shaving
Larson D.L.
Aesthet Surg J. Jul;31(5):552-559, 2011.

Objective evaluation of patients with palmar hyperhidrosis submitted to two levels of sympathectomy: T3 and T4
Ishy A., de Compos J.R.M., Wolosker N., Kauffman P., Tedde M.L., Chiavoni A.R. and Janete F.B.
Interact Cardiovasc Thorac Surg, Apr;12(4):545-8, 2011.

Effect of itch, scratching and mental stress on autonomic nervous system function in atopic dermatitis
Tran B.W., Papoiu A.D.P., Russoniello C.V., Wang H., Patel T.S., Chan Y.-H. and Yosipovitch G.
Acta Derm Venereol, Jun;90(4):354-361, 2010.

Endoscopic lumbar sympathectomy for plantar hyperhidrosis
Rieger R., Pedevilla S. and Pöchlauer S.
Br J Surg, Dec; 96(12):1422-1428, 2009.

Effects of low humidity and high air velocity in a heated room on physiological responses and thermal comfort after bathing: An experimental study
Hashiguchi N. and Tochihara Y.
Int J Nurs Stud, Feb;46(2):172–180, 2009.

Primary palmoplantar hyperhidrosis and thoracoscopic sympathectomy: A new objective assessment method
Tetteh H.A., Groth S.S., Kast T., Whitson B.A., Radosevich D.M., Klopp A.C., D’Cunha J., Maddaus M.A. and Andrade R.S.
Ann Thorac Surg, Jan;87:1:267-275, 2009.

Increased carbonyl protein levels in the stratum corneum of the face during winter
Kobayashi Y., Iwai I., Akutsu N. and Hirao T.
Int J Cosmet Sci, 30:35–40, 2008.

Endoscopic lumbar sympathectomy for women: Effect on compensatory sweat
Loureiro M.P., de Campos J.R.M., Kauffman P., Jatene F.B., Weigmann S. and Fontana A.
Clinics, 63(2):189-96, 2008.

Upper limb musculoskeletal disorders – With special reference to sympathetic nerve functions and tactile sensation
Ming Z.
Kuopio University Publications D. Medical Sciences 405. 2007. 91 p. MD Thesis.

Retroperitoneoscopic lumbar sympathectomy for the treatment of plantar hyperhidrosis: technique and preliminary findings
Rieger R. and Pedevilla S.
Surg Endosc, Jan;21(1):129-35, 2007.

Physiological and subjective responses to low relative humidity in young and elderly men
Sunwoo Y., Chou C., Takeshita J., Murakami M. and Tochihara Y.
J Physiol Anthropol, 25:229-238, 2006.

Physiological and subjective responses to low relative humidity
Sunwoo Y., Chou C., Takeshita J., Murakami M. and Tochihara Y.
J Physiol Anthropol, 25:7-14, 2006.

Abstracts

Safety and efficiancy of dual 924 and 975 nm wavelength laser for the treatment of primary axillary hyperhidrosis
Chasin M.
Lasers Surg Med, Mar; 44(S24):1-94, 2012. American Society of Laser Medicine and Surgery Abstracts. Published online Mar 15, 2012.

Objective evaluation of thoracoscopic sympathectomy for palmar hyperhidrosis
Tetteh H.A., Kast T., Maddaus M.M., Whitson B.A., Groth S.S., Radosevich D.M. and Andrade R.S.
44th Annual Meeting, The Society of Thoracic Surgeons, Jan 28-30, 2008, p. 176

Measurement of the amount of average hydrosis for giving data for scientific comparison
Pedevilla S. and Rieger R.
Presented in 7th International Symposium on Sympathetic Surgery, 20–22 March 2007
Clinical Autonomic Research, Apr;17(2), 2007.

Veterinary dermatology and skin behaviour, treatment and nutrition, Zoology

Effect of Physiological Changes in the Skin on Systemic Absorption of Tacrolimus Following Topical Application in Rats
Hazama Y., Maekawa T., Miki R., Oshima S., Egawa Y., Morimoto K. and Sekia T.
Biol Pharm Bull. 39:343-352, 2016.

In vivo assessment of the effect of taxifolin glycoside on atopic dermatitis-like skin lesions using biomedical tools in NC/Nga mice
Kim J.Y., Lee O.S., Ha S., Kim J.H., Park G., Kim J.K. and Oh C.H.
Clin Exp Dermatol, Jul;40(5):547-55, 2015.

Nalfurafine suppresses pruritogen- and touch-evoked scratching behavior in models of acute and chronic itch in mice
Akiyama T., Carstens M.I., Piecha D., Steppan S. and Carstens E.
Acta Derm Venereol, Feb;95(2):147-50, 2015.

An emulsion restores the skin barrier by decreasing the skin pH and inflammation in a canine experimental model
Pin D., Bekrich M., Fantini O., Noel G. and Vidémont E.
J Comp Pathol, Aug-Oct;151(2-3):244-54, 2014.

Transepidermal water loss in cats: comparison of three differently clipped sites to assess the influence of hair coat on transepidermal water loss values
Momota Y., Shimada K., Takami A., Akaogi H., Takasaki M., Mimura K., Azakami D., Ishioka K., Nakamura Y. and Sako T.
Vet Dermatol, Aug;24(4):450-2, 2014.

Clinical use of a ceramide-based moisturizer for treating dogs with atopic dermatitis
Jung J.-Y., Nam E.-H., Park S.-H., Han S.-H. and Hwang C.-Y.
J Vet Sci, 14(2):199-205, 2013.

Pilot study to evaluate the effect of topical dimethicone on clinical signs and skin barrier function in dogs with naturally
occurring atopic dermatitis
Pellicoro C., Marsella R. and Ahrens K.
Vet Med Int, epub Apr 17, 2013.

Transepidermal water loss in cats: comparison of three differently clipped sites to assess the influence of hair coat on transepidermal water loss values
Momota Y., Shimada K., Takami A., Akaogi H., Takasaki M., Mimura K., Azakami D., Ishioka K., Nakamura Y. and Sako T.
Vet Dermatol, Aug;24(4):450-2, 2013.

Dissolving polymer microneedle patches for rapid and efficient transdermal delivery of insulin to diabetic rats
Ling M.-H. and Chen M.-C.
Acta Biomater, Nov;9(11):8952-8961, 2013.

Transdermal delivery of methotrexate for pediatrics using silicon microneedles
Abla M.J., Chaturvedula A., O’Mahony C. and Banga A.K.
Ther Deliv, May;4(5):543-31, 2013.

The effect of Psoroptes ovis infestation on ovine epidermal barrier function
Stoeckli M.R., McNeilly T.N., Frew D, Marr E.J., Nisbet A.J., van den Broek A.H.M. and Burgess S.T.G.
Vet Res, 44, 2013.

Compensation of cATSCs-derived TGFb1 and IL10 expressions was effectively modulated atopic dermatitis
Jee M.K., Im Y.B., Choi J.I. and Kang S.K.
Cell Death Dis, 4;e497, 2013.

Effects of Korean red ginseng extract on the prevention of atopic dermatitis and its mechanism on early lesions in a murine model
Cho E. and Cho S.H.
J Ethnopharmacol, Vol145(1):294–302, 2013.

Flii neutralizing antibodies improve wound healing in porcine preclinical studies
Jackson J.E., Kopecki Z., Adams D.H. and Cowin A.J.
Wound Repair Regen, Vol 20(4):523–536, 2012.

Rheological characterization of a xanthan–galactomannan hydrogel loaded with lipophilic substances
Koop H.S., Da-lozzo E.J., de Freitas R.A., Franco C.R.C., Mitchell D.A. and Silveira J.L.M.
J Pharm Sci, Vol 101(7):2457–2467, 2012.

Evaluation of the effect of a 0.0584% hydrocortisone aceponate spray on clinical signs and skin barrier function in dogs with atopic dermatitis
Nam E.-H., Park S.-H., Jung J.-Y., Han S.-H., Youn H.-Y., Chae J.-S. and Hwang C.-Y.
J Vet Sci, 13(2):187-191, 2012.

Mouse model of touch-evoked itch (Alloknesis)
Akiyama T., Carstens M.I., Ikoma A., Cevikbas F., Steinhoff M. and Carstens E.
J Invest Dermatol, Jul;132:1886-1891, 2012.

Transcutaneous DNA immunization following waxing-based hair depilation
Sloat B.R., Kiguchi K., Xiao G., DiGiovanni J., Maury W. and Zhengrong Cui Z.
J of Control Release, Vol 157(1):94–102, 2012.

Evaluation of nutritional status and skin condition among elderly residents in a long-term care hospital
Iizaka S., Jiao L., Sugama J., Minematsu T., Oba M., Matsuo J., Tabata K., Sugiyama T. and Sanada H.
J Nutr Health Aging, Vol 16(1):107-111, 2012.

Gastrointestinal microbiota and local inflammation during oxazolone-induced dermatitis in BALB/cA mice
Lundberg R., Clausen S.K., Pang, W., Nielsen D.S., Möller K., Josefsen K.E. and Hansen A.K.
Comp Med, Vol 62;5:371-380(10), 2012.

Hydric balance and locomotor performance of an anuran (Rhinella marina) invading the Australian arid zone
Tingley R., Greenlees M. J. and Shine R.
Oikos, Dec;121(12):1959-65, 2012.

A novel mouse model of atopic dermatitis with epicutaneous allergen sensitization and the effect of Lactobacillus rhamnosus
Kim H.-J., Kim Y.-J., Kang M.-J., Seo J.-H., Kim H.-Y., Jeong S.J., Lee S.-H., Kim J.-M. and Hong S.-J.
Exp Dermatol, Vol 21(9):672-675, 2012.

Fabrication of pseudo-ceramide-based lipid microparticles for recovery of skin barrier function
Kim D.-H., Park W.R., Kim J.H., Cho E.C., An E.J., Kim J.-W. and Oh S.G.
Colloids Surf B Biointerfaces, Jun;1(94):236-241, 2012.

Characterization of the canine skin barrier restoration following acute disruption by tape stripping
Vidémont E., Mariani C., Vidal S. and Pin D.
Vet Dermatol, Apr;23(2):103-9, 2012

Decrease of ceramides with very long–chain fatty acids and downregulation of elongases in a murine atopic dermatitis model
Part Y.H., Jang W.H., Seo J.A., Park M., Kim D.K. and Lim K.M.
J Invest Dermatol, 132:476-479, 2011.

A phase 2, double-blind, randomized, placebo-controlled trial of a novel nutritional supplement product to promote healthy skin
Dayan S.H., Arkins J.P., Sharma V., Paterson E. and Barnes D.
J Drugs Dernatol, Vol 10(10):1106-1114, 2011.

Cutaneous water loss and lipids of the stratum corneum in two syntopic species of bats
Muñoz-Garcia A., Ro J., Reichard J.D., Kunz T.H. and Williams J.B.
Comp Biochem Physiol A Mol Integr Physiol, Feb;161(2):208-215, 2012.

Spontaneous itch in the absence of hyperalgesia in a mouse hindpaw dry skin model
Akiyama T., Carstens M.I. and Carstens E.
Neuroscience Letters, Oct 22;484(1):62-75, 2010.

Technical note: Development of a self-contained, indwelling rectal temperature probe for cattle research
Reuter R.R., Carroll J.A., Hulbert L.E., Dailey J.W. and Galyean M.L.
J Anim Sci, Oct;88(10):3291-3295, 2010.

Beneficial effect of dietary epigallocatechin-3-gallate on skin via enhancement of antioxidant capacity in both blood and skin
Jeon H.Y., Kim J.K., Seo D.B., Cho S.Y. and Lee S.J.
Skin Pharmacol Physiol, 23(6):283-289, 2010.

Metabolic adaptations to heat stress in growing cattle
O’Brien M.D., Rhoads R.P., Sanders S.R., Duff G.C. and Baumgard L.H.
Domestic Animal Endocrinology, Feb;38(2):86-94, 2010.

Induced keratinocyte hyper-proliferation in α2β1 integrin transgenic mice results in systemic immune cell activation
Teige I., Backlund A., Svensson L., Kvist P.H., Petersen T.K. and Kemp K.
International Immunopharmacology, Jan;10(1):107-14, 2010.

Transepidermal water loss, stratum corneum hydration and transmission electron microscope observation on acetone damaged canine skin barrier model
Oh W., Park S. and Oh T.
J Vet Clin, 27(2):142-146, 2010.

Mapping of the dog skin based on biophysical measurements
Oh W.-S. and Oh T.-H.
Vet Derm, 21:367–372, 2010.

Evaluation of a hand-held evaporimeter (VapoMeter®) for the measurement of transepidermal water loss in healthy dogs
Lau-Gillard P. J., Hill P. B., Chesney C. J., Budleigh C. and Immonen A.
Vet Derm, 21:136–145, 2010.

Evaluation of physiological and blood serum differences in heat-tolerant (Romosinuano) and heat-susceptible (Angus) Bos taurus cattle during controlled heat challenge
Scharf B., Carroll J.A., Riley D.G., Chase C.C. Jr., Coleman S.W., Keisler D.H., Weaber R.L. and Spiers D.E.
J Anim Sci, Jul;88(7):2321-36, 2010.

Auswirkung von lokal applizierten Fettsäuren auf den epidermalen Wasserverlust, Pruritus und klinischen Hautzustand atopischer und gesunder Hunde
Tretter S.
PhD Thesis, Ludwig-Maximilians-Universität München, 2010.

Measurement of transepidermal water loss from clipped and unclipped anatomical sites on the dog
Oh W.-S. and Oh T.-H.
Aust Vet J, Oct;87(10):409-412, 2009.

Effects of a supplemental yeast culture on heat-stressed lactating Holstein cows
Shwartz G., Rhoads M.L., VanBaale M.J., Rhoads R.P. and Baumgard L.H.
J Dairy Sci, Mar;92(3):935-942, 2009.

Water exchange and permeability properties of skin in three species of amphibious sea snakes (Laticauda spp.)
Lillywhite H.B., Menon J.G., Menon G.K., Sheehy 3rd C.M. and Tu M.C.
J Exp Biol, 212:1921-1929, 2009.

Profile of the bovine acute-phase response following an intravenous bolus-dose lipopolysaccharide challenge
Carroll J.A., Reuter R.R., Chase Jr C.C., Coleman S.W., Riley D.G., Spiers D.E., Arthington J.D. and Galyean M.L.
Innate Immunity, 15:2:81-89, 2009.

Chronic ethanol ingestion alters xenobiotic absorption through the skin: Potential role of oxidative stress
Brand R.M. and Jendrzejewski J.L.
Food Chem Toxicol, 46:1940-1948, 2008.

Olopatadine ameliorates rat experimental cutaneous inflammation by improving skin barrier function
Tamura T., Matsubara M., Amano T. and Chida M.
Pharmacology; 81:118-126, 2008.

Potential mechanisms by which a single drink of alcohol can increase transdermal absorption of topically applied chemicals
Brand R.M., Jendrzejewski J.L. and Charron A.R.
Toxicology, Jun 25;235(3):141-149, 2007.

Olopatadine hydrochloride accelerates the recovery of skin barrier function in mice
Amano T., Takeda T., Yano H. and Tamura T.
Br J Dermatol, May;156(5):906-912, 2007.

Cutaneous water loss and lipids of the stratum corneum in dusky anticirds, a lowland tropical bird
Munos-Garcia A. and Williams J.B.
The Condor, 109:59-66, 2007.

Transepidermal water loss reflects permeability barrier status: validation in human and rodent in vivo and ex vivo models
Fluhr J.W., Feingold K.R. and Elias P.M.
Exp Dermatol, Jul;15(7):483-92, 2006.

Abstracts

Physiological values of skin surface pH and transepidermalwater loss in healthy cats according to the breed and age.
Mariani C., Feugier A., Vidal S., and Biourge V.
25th Annual Congress of the ECVD-ESVD, Sep 8-10, 2011, Brussels, Belgium.

Investigation of the efficacy of a moisturizer on the skin barrier recovery in a canine model of mechanical chronic barrier disruption.
Videmont E., Ghibaudo G. and Pin D.
25th Annual Congress of the ECVD-ESVD, Sep 8-10, 2011, Brussels, Belgium.
Abstract.

Skin permeability and water relations of sea snakes
Lillywhite H.B., Babonis L.S., Shhehy C.M. and Tu M.-C.
FASEB J, 22:1239.18, 2008.

Sweating rate of dairy cows under shade and sunny environments
Gebremedhin K.G., Hillman P.E., Lee C.N. and Collier R.J.
Presented at American Society of Agricultural and Biological Engineers Annual Meeting, 2007.

Regional differences in sweat rate response of steers to short-term heat stress
Spiers D.E., Wax L.E., Scharf B. and Aiken G.E.
J Anim Sci, Vol 84, Suppl 1/J Dairy Sci, Vol 89, Suppl 1: 303-304, 2006.

Effects of ambient temperature and solar radiation on skin evaporative water loss in dairy cattle
Pollar B.C., Dwyer, M.E., Fitzgerald A.C., Gentry P.C., Henderson D.A. and Collier R.J.
J Anim Sci, Vol 82, Suppl 1/J Dairy Sci, Vol 87, Suppl 1/Poult Sci Vol 83, Suppl 1: 198, 2006.

Impact of alcohol consumption on the skin as determined by non-invasive bioengineering tools
Brand R.M., Jendrzejewski J.L. and Charron A.R.
Society of Toxicology Meeting, March 2006.

Effects of ambient temperature and solar radiation on skin evaporative water loss in dairy cattle
Pollard, B. C., Dwyer, M. E., Fitzgerald, A. C., Gentry, P. C., Henderson, D. A. and Collier, R. J.
J Anim Sci, Vol 82, Suppl. 1/ J Dairy Sci, Vol 87, Suppl. 1/ Poult Sci, Vol 83, Suppl. 1. 198, 2004.

Heat dissipation in winter-acclimated lactating cows and non-lactating heifers subjected to increased ambient temperature and solar radiation in Arizona
Pollard, B. C., Annen, E. A., Baumgard, L. H., Cheatham, R. C., Estheimer, M. D., Dwyer, M. E., Fitzgerald, A. C., Halfliger, H. C., Moore, C. E., Kay, J. K., Mendivil, O. B., Gentry, P. C., Henderson, D. A., Steining, C. M. and Collier, R. J.
J Anim Sci, Vol 82, Suppl. 1/ J Dairy Sci, Vol 87, Suppl. 1/ Poult Sci, Vol 83, Suppl. 1. 461, 2004.

In-vitro studies

Suitability of skin integrity tests for dermal absorption studies in vitro
Guth K., Schäfer-Korting M., Fabian E., Landsiedel R. and van Ravenzwaay B.
Toxicol In Vitro, Feb;29(1):113-23, 2015.

Hydrogel-forming microneedles prepared from “super swelling” polymers combined with lyophilised wafers for transdermal drug delivery
Donnelly R.F., McCrudden M.T., Zaid Alkilani A., Larrañeta E., McAlister E., Courtenay A.J., Kearney M.C., Singh T.R., McCarthy H.O., Kett V.L., Caffarel-Salvador E., Al-Zahrani S. and Woolfson A.D.
PLoS One, 2014 Oct 31;9(10):e111547. doi: 10.1371/journal.pone.0111547. eCollection 2014.

Effects of eight vehicles on transdermal lidocaine penetration in sheep skin in vitro
Bayldon W., Narishetty S., De Rose G., Rothwell J. and Mills P.C.
J Vet Pharmacol, epub Aug 28, 2013.

Role of partition coefficients in determining the percutaneous penetration of salicylic acid and formaldehyde under varying occlusion durations
Hafeez F., Chiang A., Hui X. and Maibach H.
Drug Dev Ind Pharm, epub Aug 12, 2013.

Human skin in vitro permeation of bentazon and isoproturon formulations with or without protective clothing suit
Berthet A., Hopf N.P., Miles A., Spring P., Charrière N., Garrigou A., Baldi I. and Vernez D.
Arch Toxicol, epub Jul 3, 2013.

Cutaneous delivery of α-tocopherol and lipoic acid using microemulsions: influence of composition and charge
Cichewicz A., Pacleb C., Connors A., Hass M.A. and Lopes L.B.
J Pharm Pharmacol, Jun;65(6):817–26, 2013.

Stratum corneum drying drives vertical compression and lipid organization and improves barrier function in vitro
Iwai I., Kunizawa N., Yagi E., Hirao T. and Hatta I.
Acta Derm Venereol, 93:138-43, 2013.

Dermal exposure to methamphetamine hydrochloride contaminated residential surfaces: Surface pH values, volatility, and in vitro human skin
Salocks C.B., Hui X., Lamel S., Qiao P, Sanborn J.R. and Maibach H.I.
Food Chem Toxicol, Vol 50(12):4436–40, 2012.

Changes in ceramides and glucosylceramides in mouse skin and human epidermal equivalents by rice-derived glucosylceramide
Shimoda H., Terazawa S., Hitoe S., Tanaka J., Nakamura S., Matsuda H. and Yoshikawa M.
J Med Food, 15(12):1064-1072, 2012.

Influence of a pore-forming agent on swelling, network parameters, and permeability of poly(ethylene glycol)-crosslinked poly(methyl vinyl ether-co-maleic acid) hydrogels: Application in transdermal delivery systems
Raj Singh T.R., Garland M.J., Migalska K., Salvador E.C., Shaikh R., McCarthy H.O., Woolfson D.A. and Donnelly R.F.
J Appl Polym Sci, Aug;125(4):2680–2694, 2012.

Rheological characterization of a xanthan-galactomannan hydrogel loaded with lipophilic substances
Koop H.S., Da-Lozzo E.J., de Freitas R.A., Franco C.R., Mitchell D.A. and Silveira J.L.
J Pharm Sci, Jul;101(7):2457-2467, 2012.

Low frequency sonophoresis mediated transdermal and intradermal delivery of ketoprofen
Herwadkar A., Sachdeva V., Taylor L.F., Silver H. and Banga A.K.
Int J Pharm, Feb;423(2):289-296, 2012.

Structure-skin permeability relationship of dendrimers
Venuganti V.V., Sahdev P., Hildreth M., Guan X. and Perumal O.
Pharm Res, Sep;28(9):2246-2260, 2011.

Enhanced dermal delivery of acyclovir using solid lipid nanoparticles
Jain S., Mistry M.A. and Swarnaker N.K.
Drug Del Trans Res, 5(1):395-406, 2011.

Skin penetration and deposition of carboxyfluorescein and temoporfin from different lipid vesicular systems: In vitro study with finite and infinite dosage application
Chen M., Liu X. and Fah A.
Int J Pharm, Apr 15;408(1-2):223-234, 2011.

Magnetophoresis for enhancing transdermal drug delivery: Mechanistic studies and patch design
Murthy, S.N., Sammeta S.M. and Bowers C.
Journal of Controlled Release, Dec 1;148(2):197-203, 2010.

Skin delivery of ferulic acid from different vesicular system
Chen M., Liu X. and Fahr A.
J Biomed Nanotechnol, Oct;6(5):577-585, 2010.

Evaluation needle length and density of microneedle arrays in the pretreatment of skin for transdermal drug delivery
Yan G., Warner K.S., Zhang J., Sharma S. and Gale B.K.
Int J Pharm, May 31; 391(1-2):7-12, 2010.

Microchannels created by sugar and metal microneedles: Characterization by microscopy, macromolecular flux and other techniques
Li G., Badkar A., Kalluri H. and Banga A. K.
J Pharm Sci, Apr;99(4):1931-41, 2010.

Transdermal iontophoretic delivery of terbinafine hydrochloride: Quantitation of drug levels in stratum corneum and underlying skin
Sachdeva V., Siddoju S., Yu Y.-Y., Kim H.D., Friden P.M. and Banga A.K.
Int J Pharm, Mar;388(1-2),24-31, 2010.

Transdermal and intradermal iontophoretic delivery of dexamethasone sodium phosphate: quantification of the drug localized in skin
Paturi J., Kim H.D., Chakraborty B., Friden P.M. and Banga A.K.
J Drug Targ, Feb;18(2):134-140, 2010.

Transdermal delivery of fentanyl from matrix and reservoir systems: Effect of heat and compromised skin
Prodduturi S., Sadrieh N., Wokovich A.M., Doub W.H., Westenberger B. J. and Buhse L.
J Pharm Sci, 99:2357–2366, 2010.

Microneedle arrays allow lower microbial penetration than hypodermic needles in vitro
Donnelly R.F., Singh T.R.R., Tunney M.M., Morrow D.I.J., McCarron P.A., O’Mahony C. and Woolfson A.D.
Pharm Res, Nov;26(11):2513–2522, 2009.

Poly(amidoamine) dendrimers as skin penetration enhancers: Influence of charge, generation, and concentration.
Venuganti V.V.K. and Perumal O.P.
J Pharm Sci, Jul;98(7):2345–2356, 2009.

OcuDrain-E™ -A noninvasive technique for reduction of intraocular pressure.
Murthy S.M., Sammeta S.M. and Vaka S.R.K.
Int J Pharm, Mar;369(1-2):92-95, 2009.

Skin penetration enhancement by a microneedle device (Dermaroller®) in vitro: Dependency on needle size and applied formulation
Badran M.M., Kuntsche J. and Fahr A.
Eur J Pharm Sci, Mar;36(4-5):511-523, 2009.

Reservoir based fentanyl transdermal drug delivery systems: effect of patch age on drug release and skin permeation
Prodduturi S., Smith G.J., Wokovich A.M., Doub W.H., Westenberger B.J. and Buhse L.
Pharm Res, 26:6, 2009.

Molecular charge mediated transport of a 13 kD protein across microporated skin
Katikaneni S., Badkar A., Nema S. and Banga A.K.
Int J Pharm, 378:93–100, 2009.

Films based on chitosan polyelectrolyte complexes for skin drug delivery:Development and characterization
Silva C.L., Pereira J.C., Ramalho A., Pais A.C.C.C. and Sousa J.J.S.
J Memb Sci, 320:268-279, 2008.

Effect of poly(amidoamine) (PAMAM) dendrimer on skin permeation of 5-fluorouracil
Venuganti V.V.K. and Perumal O.P.
Int J Pharm, 361:230-238, 2008.

Interaction of lipid nanoparticles with human epidermis and an organotypic cell culture model
Kuntsche J., Bunjes H., Fahr A., Pappinen S., Rönkkö S., Suhonen M. and Urtti A.
Int J Pharm, 354:180-195, 2008.

Qualitative and quantitative comparison of heat separated epidermis and dermatomed skin in percutaneous absorption studies
Atrux-Tallau N., Pirot F., Falson F., Roberts M.S. and Maibach H.I.
Arch Dermatol Res, 299:507-511, 2007.

In vitro human skin model to evaluate water permeability and determine wound dressings’ occlusivity
Zhai X., Yokota M. and Maibach H.I.
Cutan Ocul Toxicol, 26(2):107-11, 2007.

Vitamin C enhances differentation of a continuous keratinocyte cell line (REK) into epidermis with normal stratum cornuem ultrasructure and functional permeability barrier
Pasonen-Seppänen S., Suhonen T.M., Kirjavainen M., Suihko E., Urtti A., Miettinen M., Hyttinen M., Tammi M. and Tammi R.
Histocem Cell Biol, 116:287-297, 2001.

Formation of permeability barrier in epidermal organotypic culture for studies on drug transport
Pasonen-Seppänen S., Suhonen T.M., Kirjavainen M., Miettinen M., Urtti A., Tammi M. and Tammi R.
J Invest Dermatol, Nov;117(5):1322-1324, 2001.

Abstracts

Comparative dermal penetration studies in human full-thickness and dermatomed skin
Guth K., Schäfer-Korting M., Fabian E., van Ravenzwaay B. and Landsiedel R.
Poster presented at Skin Forum 12th Annual Meeting; 28-29 Mar 2011.

Validation articles

Validating a new device for measuring tear evaporation rates
Rohit A., Ehrmann K., Naduvilath T., Willcox M. and Stapleton F.
Ophthalmic Physiol Opt, Jan;34(1):53-62, 2014.

International guidelines for the in vivo assessment of skin properties in non-clinical settings: Part 2. transepidermal water loss and skin hydration
du Plessis J., Stefaniak A., Eloff F., John S., Agner T., Chou T.-C., Nixon R., Steiner M., Franken A., Kudla I. and Holness L.
Skin Res Technol, Aug;19(3):265-78, 2013.

Side-by-side comparison of an open-chamber (TM 300) and a closed-chamber (Vapometer™) transepidermal water loss meter
Steiner M., Aikman-Green S., Prescott G.J. and Dick F.D.
Skin Res Technol, Aug;17(3):366-72, 2011.

Tape-stripping method in man: comparison of evaporimetric methods
Zhai H., Dika E., Goldovsky M. and Maibach H.I.
Skin Res Technol, May;13(2):207-10, 2007.

Measurement of transepidermal water loss by closed-chamber systems
Nuutinen J.
in Serup J., Jemec G.B.E. and Grove G., (eds.), Handbook of non-invasive methods and the skin, 2nd edition, CRC Press, Boca Raton, FL, pp.
393-396, 2006.

Comparative evaporimetry in man
Shah J.H., Zhai H. and Maibach H.I.
Skin Res Technol, Aug;11(3):205-8, 2005.

Validation of the VapoMeter, a closed unventilated chamber system to assess transepidermal water loss vs. the open chamber Tewameter
De Paepe K., Houben E., Adam R., Wieswmann F. and Rogiers V.
Skin Res Technol, Feb;11(1):61-9, 2005.

Water loss through lip, nail, eyelid skin, scalp skin and axillar skin measured with a closed-chamber evaporation principle
Nuutinen J., Harvima I., Lahtinen M.-R. and Lahtinen T.
Br J Dermatol, 148:839-841, 2003.

A closed unventilated chamber for the measurement of transepidermal water loss
Nuutinen J., Alanen E., Autio P., Lahtinen M-R., Harvima I. and Lahtinen T.
Skin Res Technol, May;9(2):85-9, 2003.

Abstracts

Applicability of the closed unventilated VapoMeter to assess transepidermal water loss (TEWL) on nasolabial skin areas
De Paepe, K., Houben, E., Adam, R., Wiesemann, F. and Rogiers, V.
Skin Res Technol, Vol 10:3, 2004.

Comparison of two methods for TEWL measurement
Shah J.H., Zhai H., Maibach H.I. and Nuutinen J.
Skin Res Technol, Vol 10, 2004.

Measurement of water evaporation rates with a closed chamber TEWL meter
Nuutinen, J., Alanen, E. and Lahtinen, T.
Skin Res Technol, Vol 9(2):183, 2003.

Contact us for more information

  • I want to ask about:

    Click here to show options